The world’s largest economies delivered more worrisome cues Monday as anxiety over the virus outbreak sent stock and oil prices plunging and closed sites from the Sistine Chapel to Saudi Arabian schools.

Shares in Asia, the Mideast and Europe, and U.S. futures were down sharply, reports on the health of the economies of Japan and China stirred more unease, and the downturn was being felt by people around the world.

“Our business is one-fifth of what it was before,” said Cheng Sheng, who helps run a food stand in Beijing that sells sausages and noodles. “There’s much less foot traffic. There are no people.”